Maternal immune activation transgenerationally modulates maternal care and offspring depression-like behavior
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چکیده
منابع مشابه
Maternal immune activation transgenerationally modulates maternal care and offspring depression-like behavior
Gestational infection is increasingly being recognized for its involvement as causative mechanism in severe developmental brain abnormalities and its contribution to the pathogenesis of psychopathologies later in life. First observations in the widely accepted maternal immune activation (MIA) model based upon the systemic administration of the viral mimetic Polyinosinic:polycytidylic acid (poly...
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Maternal immune activation (MIA) is a well-established model for the investigation of the deleterious effects of gestational infection on offspring mental health later in life. Hence, MIA represents a critical environmental variable determining brain development and the depending neural and behavioral functions in the progeny. Transgenerational transmission of some of the effects of MIA has bee...
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ژورنال
عنوان ژورنال: Brain, Behavior, and Immunity
سال: 2017
ISSN: 0889-1591
DOI: 10.1016/j.bbi.2016.10.016